Clearsynth receives Government Backing to Advance India’s Deuterated Chemical Production Driving India’s Leadership in High-Value Chemical Technology

Pioneering Deuteration. Powering Self-Reliance

Clearsynth Labs Limited has obtained grants from the Technology Development Board (TDB), which is part of the  Department of Science and Technology (DST), Government of India, to build the nation's first dedicated manufacturing facility for the commercial-scale production of deuterated reagents, intermediates, and building blocks.  This is a significant step towards enhancing India's capabilities in advanced specialty chemicals. 

The initiative comes at a pivotal moment as the demand for deuterated compounds continues to grow globally due to  their vital uses in high-tech industries such as fiber optics, semiconductors, OLEDs, Defense and pharmaceuticals.  India has a robust pharmaceutical manufacturing ecosystem, but lacks high-purity, scalable domestic technologies,  it’s until now been dependent on imports for these specialized but strategically significant chemicals. 

TDB's support will help create a unique indigenous facility that will make India a strong supplier of high-value deuterated compounds. This project supports the Make in India and Atmanirbhar Bharat missions, focusing on self reliance in the chemical sector. Clearsynth’s partnership with the Heavy Water Board, (Department of Atomic Energy,  GOI) for continued access to heavy water, ensures cost competitiveness and the ability to grow to meet local and global needs.

The project is anticipated to make a substantial contribution with TDB's assistance in the following areas: 

❖ Developing domestic capabilities in isotope-labeled compounds 

❖ Conserving foreign exchange by displacing imports 

❖ Promoting innovation through IP generation 

❖ Establishing highly skilled jobs in chemical manufacturing and research and development ❖ Establishing India as a dependable worldwide supplier in a high-value niche market. 

Mr. Vijay Ambati, MD & CEO of Clearsynth Labs Limited, stated, "This initiative marks a significant milestone for  India's specialty chemicals industry." "We are thankful for TDB and DST's support in realizing this vision, and we are  proud to contribute to India's scientific and manufacturing capabilities." 

Shri Rajesh Kumar Pathak, Secretary, TDB, spoke during the deal signing and stated, "This project positions India to capitalize on the rapidly expanding global market for deuterated compounds with widespread industrial applications. Bulk production of these materials is a strategically significant opportunity, and with TDB's assistance, a domestic,  top-tier manufacturing base may be established in this rapidly expanding industry.” 

Collaboration with HWB

In the year 2018, the Heavy Water Board recognized the potential of non-nuclear applications and took the first step in collaborating with two Indian Private organizations to encourage the development and manufacturing of deuterated products. The Objective  was to substitute Imports and promote its exports 

Note on Deuterium Chemistry

Deuterium is a hydrogen isotope with one proton and one neutron in its nucleus. Deuterium oxide, also known as  "heavy water," is a type of water (H2O) with a larger proportion of the deuterium isotope (2H or D) than conventional water. 

▪ Atomic mass twice heavier than hydrogen 

▪ Vibrational zero energy – lower than C-H bond 

▪ More stable than C-H bond 

▪ Longer than C-H bond 

▪ Activation energy required to break C-D bond is higher 

▪ Lower kinetic rate

About Us 

Clearsynth is a global leader in the field of specialty chemicals, offering world-class expertise in the synthesis of deuterated compounds, reference standards, stable isotope-labeled compounds, and custom chemical solutions. With  a focus on innovation, quality, and sustainability.  

Clearsynth partners with industries worldwide to support cutting-edge research and manufacturing. It focuses on innovative organic chemistry and the synthesis of novel complex molecules, stable isotope labeled compounds,  metabolites, impurities, glucuronides, chiral compounds, conjugate impurities, and radioactive labeled compounds. 

Clearsynth is a significant player in the deuterium market, expanding its manufacturing capabilities and offerings to meet the growing global demand for deuterated compounds in various industries, including pharmaceuticals, advanced materials, and research applications. The products find applications in various industries, including pharmaceuticals, defense, semiconductors, OLEDs, and fiber optics.