Silo Pharma Secures Australian Patent For SPC-15 PTSD Treatment; Reinforces Intranasal PTSD Therapy Development
Silo Pharma secures Australian patent for SPC-15, advancing stress-prevention therapy for PTSD and anxiety.
Breaking News
Sep 05, 2025
Vaibhavi M.

Silo Pharma, Inc. announced that IP Australia has granted patent number 2020271839 to Columbia University for an invention related to stress prevention using serotonin 4 receptor agonists. The patent is exclusively licensed to Silo, further strengthening the company’s intellectual property portfolio.
“This patent further strengthens our global IP portfolio for SPC-15, protecting its novel approach to preventing stress-induced disorders and enhancing stress resilience,” said Silo CEO Eric Weisblum. “The claims further strengthen and support our plans for clinical trial development of SPC-15 as an innovative therapeutic for PTSD.”
The newly granted patent provides expanded protection for SPC-15, Silo’s lead intranasal therapy for post-traumatic stress disorder (PTSD), which was originally developed by Columbia University. SPC-15 targets the serotonin 5-HT4 receptor and is designed to address psychiatric conditions linked to stress, including PTSD and anxiety.
Silo Pharma holds exclusive global rights to develop and commercialize SPC-15 and is collaborating with Columbia University on preclinical research. With potential eligibility for the FDA’s streamlined 505(b)(2) regulatory pathway, SPC-15 represents a promising candidate to accelerate development and approval timelines in addressing critical unmet needs in mental health.