Sionna Therapeutics Takes Over Key Cystic Fibrosis Treatments From AbbVie

Sionna Therapeutics, headquartered in Boston, USA, revealed today that it has secured exclusive global rights to develop and market several clinical-stage compounds under a new licensing agreement with pharmaceutical giant AbbVie (NYSE: ABBV). Founded in 2019, Sionna Therapeutics is a clinical-stage life sciences company focused on creating innovative and unique treatments for cystic fibrosis (CF). The company was established with a substantial $111 million Series B financing. As part of the agreement with AbbVie, Sionna will take over the development of three cystic fibrosis treatments: galicaftor, a TMD1-targeted CFTR corrector; navocaftor, a CFTR potentiator; and ABBV-2851, a Phase 1 TMD1-targeted corrector. Both galicaftor and navocaftor have successfully completed Phase II trials.