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Recursion Doses First Patient in Phase 2 Study of REC-994 for Cerebral Cavernous Malformation

Recursion doses first patient in Phase 2 trial of REC-994, a potential treatment for CCM.

Mrudula Kulkarni
By Mrudula Kulkarni
Managing Editor - Pharma Now
Oct 23, 2024Updated Jun 26, 2025 · 2 min read
Recursion Doses First Patient in Phase 2 Study of REC-994 for Cerebral Cavernous Malformation
https://facts.net/lifestyle/health/20-facts-about-brain-cavernous-angioma/
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Reviewed by Mrudula Kulkarni, Managing Editor - Pharma Now

Recursion, a company focused on using technology to accelerate drug discovery, has announced that the first patient has been dosed in their Phase 2 clinical trial. This study is evaluating the effectiveness of REC-994, a drug aimed at treating cerebral cavernous malformation (CCM), a condition characterized by abnormal blood vessels in the brain that can lead to seizures, strokes, and other serious neurological issues. The dosing of the first patient marks a significant milestone in the development of potential treatments for this challenging condition.

The Phase 2 trial will assess the safety, tolerability, and efficacy of REC-994 in patients with symptomatic CCM. Recursion is hopeful that this drug can provide a much-needed therapy for those affected by this rare and debilitating disease. The company’s approach, leveraging machine learning and advanced computational techniques, allows for a more efficient and thorough investigation of potential treatments like REC-994.

Recursion's CEO expressed excitement about reaching this stage, emphasizing the potential impact of their drug discovery platform on rare diseases like CCM. The company’s focus on blending technology with biology is paving the way for innovative treatments that could make a real difference in patients' lives. The progress of this trial will be closely monitored as Recursion continues to push forward in its mission to revolutionize the way rare diseases are treated.

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Mrudula Kulkarni
Written by
Mrudula Kulkarni
Managing Editor - Pharma Now

My international experience as a researcher in Taiwan for three years has equipped me with a global perspective, enabling me to create content that resonates with an international audience.



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