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Semnur Pharmaceuticals to go public in SPAC deal of up to $2 billion with Denali Capital

Semnur Pharma to go public via SPAC merger with DECA, aiming to advance non-opioid pain treatment.

Mrudula Kulkarni
By Mrudula Kulkarni
Managing Editor - Pharma Now
Jul 03, 2024Updated Jun 26, 2025 · 2 min read
Semnur Pharmaceuticals to go public in SPAC deal of up to $2 billion with Denali Capital
https://www.linkedin.com/company/denalicapital
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Reviewed by Mrudula Kulkarni, Managing Editor - Pharma Now

Semnur Pharmaceuticals announced on Tuesday its intention to go public via a merger with Denali Capital Acquisition Corp (DECA.O), a special purpose acquisition company (SPAC). This pre-transaction equity deal is valued at up to $2 billion. Semnur, a subsidiary of Scilex Holding (SCLX.O) based in California, specializes in developing non-opioid pain treatments.

If the merger proceeds, the newly combined entity will retain the name Semnur Pharmaceuticals, with Scilex Holding remaining the majority shareholder. Shareholder approval from the SPAC is expected to be sought in the latter half of 2024.

The funds from the transaction will be allocated towards advancing Semnur’s leading drug candidate, SP-102, which is in late-stage clinical trials for treating patients with moderate-to-severe chronic radicular pain or sciatica. Sciatica involves the irritation, inflammation, pinching, or compression of nerves extending from the lower back down to the legs.

SPACs are entities that raise capital through an initial public offering (IPO) and hold the funds in trust to merge with a private company, thereby taking it public. Typically, SPACs have a two-year period from their IPO to complete a merger.

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Mrudula Kulkarni
Written by
Mrudula Kulkarni
Managing Editor - Pharma Now

My international experience as a researcher in Taiwan for three years has equipped me with a global perspective, enabling me to create content that resonates with an international audience.



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